New Model-Based Bioequivalence Statistical Approaches for Pharmacokinetic Studies with Sparse Sampling

In conventional pharmacokinetic (PK) bioequivalence evaluation, two one-sided exams (TOST) are performed on the realm beneath the concentration-time curve and the maximal focus derived utilizing a non-compartmental strategy. When wealthy sampling is unfeasible, a model-based (MB) strategy, utilizing nonlinear blended impact fashions (NLMEM) is feasible. Nonetheless, MB-TOST utilizing asymptotic commonplace errors (SE) presents elevated sort I error when asymptotic situations don’t maintain.

On this work, we suggest three different calculations of the SE based mostly on (i) an adaptation to NLMEM of the correction proposed by Gallant, (ii) the a posteriori distribution of the therapy coefficient utilizing the Hamiltonian Monte Carlo algorithm, and (iii) parametric random results and residual errors bootstrap. We consider these approaches by simulations, for two-arms parallel and two-period, two-sequence cross-over design with wealthy (n = 10) and sparse (n = 3) sampling beneath the null and the choice hypotheses, with MB-TOST. All new approaches appropriate for the inflation of MB-TOST sort I error in PK research with sparse designs.

The strategy based mostly on the a posteriori distribution seems to be the very best compromise between managed sort I errors and computing occasions. MB-TOST utilizing non-asymptotic SE controls sort I error fee higher than when utilizing asymptotic SE estimates for bioequivalence on PK research with sparse sampling.

A set-dose mixture (FDC) product of a selective sodium-glucose cotransporter 2 inhibitor ertugliflozin and immediate-release metformin is authorised for sort 2 diabetes mellitus in the US, European Union nations, Canada, and different nations. Two research have been performed to evaluate the bioequivalence of metformin within the ertugliflozin/metformin FDC tablets to the corresponding doses of Canadian-sourced metformin (Glucophage) coadministered with ertugliflozin.

Simulation Knowledgeable Design and Efficiency of In Vitro Bioequivalence Trials for Particle Measurement Distributions

This research used statistical simulations to analyze the efficiency of the inhabitants bioequivalence take a look at utilized to image-based particle dimension measurements (reminiscent of morphologically directed Raman spectroscopy) and strategies for designing in vitro bioequivalence trials utilizing prior data. Simulations of in vitro inhabitants bioequivalence trials have been performed throughout a variety of consultant D50 (number-weighted median particle diameter from a log-normal particle dimension distribution) and span (which is outlined as [Formula: see text] the place D90 and D10 are the number-weighted 90th and 10th percentiles in particle diameters sampled from a log-normal particle dimension distribution) values respectively.
The efficiency of the inhabitants bioequivalence take a look at within the simulations was pushed by an interaction between total take a look at variability and the widening or narrowing of the bioequivalence area attributable to variance phrases within the take a look at statistic definition. These findings have been dependent upon variations within the variability of D50 and span and should generalise to a wider vary of in vitro metrics.
Trial design optimisation utilizing energy and assurance approaches adopted patterns in keeping with these findings. As extra novel scientific strategies are utilized to the event of complicated generic merchandise, the procedures outlined on this research could also be used on the inception stage of future in vitro bioequivalence trials to cut back the chance of conducting pricey trials with low possibilities of success.
 New Model-Based Bioequivalence Statistical Approaches for Pharmacokinetic Studies with Sparse Sampling
New Model-Based Bioequivalence Statistical Approaches for Pharmacokinetic Studies with Sparse Sampling

Detection of information manipulation in bioequivalence trials

In recent times regulators have documented how pharmaceutical corporations or medical analysis organisation can manipulate bioequivalence trial information for non-approvable formulations by performing an interim evaluation adopted by re-analysis of pharmacokinetic profiles beneath new topic aliases, with a swap of Check and Reference and/or dilutions.
The web impact is that time estimates for failing merchandise will probably be pressured artifically in direction of 1 and that trials will cross the take a look at for bioequivalence. This isn’t detectable by any pharmacopoeial technique, and isn’t addressed by widespread evaluation practices at companies. This paper goals at demonstrating how the alerts of such fraudulent research conduct could be detected.
The approaches offered are known as “Buster” and “SaToWIB” routines; these are laptop packages which have been used extensively by regulators to detect alerts of fraud however they haven’t been described within the public area. The Buster routines visualize tendencies within the type of partial statistics, residual plots, cumulative confidence intervals, cumulative imply squared errors, and extra. Runs exams on the signal of the residuals might represent a possible take a look at for the manipulation. It’s noteworthy that in 2020, regulators within the European Union have publicly begun questioning trial validity on foundation of PK profile similarity.

Horse IgG (Fab)

31C-CH0810 2 mg
EUR 408
Description: Purified Horse IgG (Fab)

Horse Immunoglobulin G (IgG) ELISA Kit

CEA544Eq-10x96wellstestplate 10x96-wells test plate
EUR 4028.46
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG) ELISA Kit

CEA544Eq-1x48wellstestplate 1x48-wells test plate
EUR 436.93
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG) ELISA Kit

CEA544Eq-1x96wellstestplate 1x96-wells test plate
EUR 572.76
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG) ELISA Kit

CEA544Eq-5x96wellstestplate 5x96-wells test plate
EUR 2217.42
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG) ELISA Kit

4-CEA544Eq
  • EUR 4089.60
  • EUR 2157.60
  • EUR 573.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Horse Immunoglobulin G (IgG) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Horse Immunoglobulin G, IgG ELISA Kit

CSB-E13882Hs-24T 1 plate of 24 wells
EUR 198
Description: Quantitative competitive ELISA kit for measuring Horse Immunoglobulin G, IgG in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Immunoglobulin G, IgG ELISA Kit

1-CSB-E13882Hs
  • EUR 600.00
  • EUR 4082.40
  • EUR 2184.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative competitive ELISA kit for measuring Horse Immunoglobulin G, IgG in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Immunoglobulin G (IgG) ELISA Kit

20-abx150448
  • EUR 6618.00
  • EUR 3536.40
  • EUR 830.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Horse Immunoglobulin G (IgG) ELISA Kit

QY-E120063 96T
EUR 573.6

Horse Immunoglobulin G(IgG)ELISA Kit

YLA0014HO-48T 48T
EUR 525

Horse Immunoglobulin G(IgG)ELISA Kit

YLA0014HO-96T 96T
EUR 645

Horse IgG (FITC)

65C-CH0802 1 mg
EUR 202.8
Description: Purified Horse IgG FITC conjugate

Horse IgG protein

31R-1055 10 mg
EUR 224.4
Description: Purified native Horse IgG protein

ELISA kit for Horse IgG (Immunoglobulin G)

ELK1350 1 plate of 96 wells
EUR 578.4
Description: A competitive Inhibition ELISA kit for detection of Immunoglobulin G from Horse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Horse IgG (H + L)

31R-1006 10 mg
EUR 172.8
Description: Horse IgG (H + L) purified protein

Horse IgG (H + L)

31R-1030 10 mg
EUR 172.8
Description: Purified Horse IgG (H + L) for use as a control or blocking reagent

Horse IgG (Fc) (HRP)

65C-CH0806 1 mg
EUR 492
Description: Purified Horse IgG (Fc) HRP conjugate

Horse IgG (Fab'2)

31C-CH0807 2 mg
EUR 406.8
Description: Purified Horse IgG (Fab'2)

Horse IgG (Fc) (FITC)

65C-CH0805 1 mg
EUR 454.8
Description: Purified Horse IgG (Fc) FITC conjugate

Horse IgG (Fab) (HRP)

65C-CH0812 1 mg
EUR 356.4
Description: Purified Horse IgG (Fab) HRP conjugate

Horse IgG (Fab) (FITC)

65C-CH0811 1 mg
EUR 296.4
Description: Purified Horse IgG (Fab) FITC conjugate

Rabbit anti Horse IgG

E61I02401 0.1mg
EUR 411.6

Horse IgG-Fc ELISA Kit, 96 tests, Quantitative

7715-Fc 1 kit
EUR 854.4

ELISA kit for Horse Immunoglobulin G,IgG

EK0119 96 tests
EUR 723.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Horse Immunoglobulin G,IgG in samples from serum, plasma, tissue homogenates and other biological fluids.

Horse Japanese Encephalitis Virus IgG (JE-IgG) ELISA Kit

YLAQ0058HO-48T 48T
EUR 525

Horse Japanese Encephalitis Virus IgG (JE-IgG) ELISA Kit

YLAQ0058HO-96T 96T
EUR 645

Horse IgG (Fab'2) (HRP)

65C-CH0809 1 mg
EUR 349.2
Description: Purified Horse IgG (Fab'2) HRP conjugate

Horse Japanese Encephlitis IgG Antibody (JE-IgG)Elisa Kit

YLAQ0040HO-48T 48T
EUR 525

Horse Japanese Encephlitis IgG Antibody (JE-IgG)Elisa Kit

YLAQ0040HO-96T 96T
EUR 645

Horse IgG (Fab'2) (FITC)

65C-CH0808 1 mg
EUR 292.8
Description: Purified Horse IgG (Fab'2) FITC conjugate

Goat anti Horse IgG Fc (HRP)

43R-IG041hrp 2 ml
EUR 524.4
Description: Goat anti Horse IgG Fc secondary antibody (HRP)

Horse anti-goat IgG, Biotin

HO30002 750 ug
EUR 271.2

Horse Immunoglobulin G (IgG) Protein

20-abx168584
  • EUR 393.60
  • EUR 243.60
  • EUR 1062.00
  • EUR 493.20
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Horse Immunoglobulin G (IgG) Protein

abx670160-10mg 10 mg
EUR 493.2

Recombivirus Horse Anti-horsepox IgG ELISA kit, 96 tests, Quantitative

AE-311140-1 1 kit
EUR 708

Horse IgG (Equine, Whole IgG, control, non-immune)-HRP Conjugate

20019-HP 0.5 mg
EUR 242.4

Horse IgG (Equine, Whole IgG, control, non-immune)-FITC Conjugate

20019-F 0.5 mg
EUR 242.4

Goat Anti Horse Igg (T) Polyclonal Antibody

DPBT-67141GH 1 mg
EUR 696

Horse Immunoglobulin G (IgG)CLIA Kit

CCA544Eq-10x96wellstestplate 10x96-wells test plate
EUR 8285.33
Description: This is Competitive Chemiluminescent immunoassay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG)CLIA Kit

CCA544Eq-1x48wellstestplate 1x48-wells test plate
EUR 787.5
Description: This is Competitive Chemiluminescent immunoassay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG)CLIA Kit

CCA544Eq-1x96wellstestplate 1x96-wells test plate
EUR 1073.57
Description: This is Competitive Chemiluminescent immunoassay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG)CLIA Kit

CCA544Eq-5x96wellstestplate 5x96-wells test plate
EUR 4471.06
Description: This is Competitive Chemiluminescent immunoassay for detection of Horse Immunoglobulin G (IgG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Horse Immunoglobulin G (IgG) CLIA Kit

4-CCA544Eq
  • EUR 8346.00
  • EUR 4471.20
  • EUR 1074.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Horse Immunoglobulin G (IgG)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Horse Immunoglobulin G (IgG) CLIA Kit

20-abx190865
  • EUR 11166.00
  • EUR 5941.20
  • EUR 1365.60
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Horse anti-goat IgG(H+L)-HRP

E22NG02-2 100ug
EUR 411.6

Horse anti-mouse IgG(H+L)-HRP

E22NM02-2 100ug
EUR 411.6

Horse anti-mouse IgG(H+L)-FITC

E22NM03-2 100ug
EUR 411.6

Horse IgG (Equine, Whole IgG, control, non-immune)-biotinylated, purified

20019-B 0.5 mg
EUR 196.8

Goat Anti Horse Igg (H/L) Polyclonal Antibody

DPBT-67136GH 1 mg
EUR 639.6

Goat Anti Horse Igg (H/L) Polyclonal Antibody

DPBT-67142GH 1 mg
EUR 696

Horse IgG Fab fragment (Equine, Whole IgG, control, non-immune), purified

20019-1-Fab 0.5 mg
EUR 196.8

Goat Anti Horse Igg (T) Polyclonal Antibody,HRP

DPBT-67140GH 1 mg
EUR 889.2

Horse IgG Fab2 fragment (Equine, Whole IgG, control, non-immune), purified

20019-1-Fab2 0.5 mg
EUR 196.8

Goat Anti Horse Igg (T) Polyclonal Antibody,FITC

DPBT-67139GH 1 mg
EUR 889.2

Horse Anti-Zaire Ebola virus glycoprotein IgG ELISA Kit, 96 tests, Quantitative

AE-320690-1 1 Kit
EUR 1220.4

Immunoglobulin G (IgG) Monoclonal Antibody (Horse)

4-MAA544Eq22
  • EUR 265.20
  • EUR 2536.80
  • EUR 642.00
  • EUR 328.80
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Immunoglobulin G (IgG)

Immunoglobulin G (IgG) Polyclonal Antibody (Horse)

4-PAA544Eq01
  • EUR 314.40
  • EUR 3296.40
  • EUR 814.80
  • EUR 397.20
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Immunoglobulin G (IgG)

Horse Anti-Diphtheria Toxoid/Toxin IgG (Fab2)

DTOX17-Fab2 100 ul
EUR 534

Horse Anti-Anthrax Protective Antigen 83 (PA83) IgG ELISA kit, 96 tests, quantitative

900-145-83G 1 Kit
EUR 927.6

Goat Anti Horse Igg (H/L) Polyclonal Antibody,HRP

DPBT-67135GH 1 mg
EUR 670.8

Horse Anti-Rabies Virus IgG (Fab2), neutralizing

RBV16-Fab2 100 ul
EUR 534

Goat Anti Horse Igg (T) Polyclonal Antibody,Alk. Phos.

DPBT-67138GH 0.5 mg
EUR 889.2

Horse Irisin ELISA Kit

EHS0009 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Horse;Sensitivity: 9.375 ng/ml

Immunoglobulin G (IgG) Monoclonal Antibody (Horse), PE

4-MAA544Eq22-PE
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with PE.

Immunoglobulin G (IgG) Polyclonal Antibody (Horse), PE

4-PAA544Eq01-PE
  • EUR 376.80
  • EUR 3478.80
  • EUR 976.80
  • EUR 476.40
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with PE.

Immunoglobulin G (IgG) Monoclonal Antibody (Horse), APC

4-MAA544Eq22-APC
  • EUR 368.40
  • EUR 3282.00
  • EUR 932.40
  • EUR 463.20
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with APC.

Immunoglobulin G (IgG) Monoclonal Antibody (Horse), Cy3

4-MAA544Eq22-Cy3
  • EUR 441.60
  • EUR 4326.00
  • EUR 1194.00
  • EUR 567.60
  • EUR 274.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with Cy3.

Immunoglobulin G (IgG) Monoclonal Antibody (Horse), HRP

4-MAA544Eq22-HRP
  • EUR 339.60
  • EUR 2864.40
  • EUR 828.00
  • EUR 421.20
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with HRP.

Immunoglobulin G (IgG) Polyclonal Antibody (Horse), Cy3

4-PAA544Eq01-Cy3
  • EUR 538.80
  • EUR 5708.40
  • EUR 1539.60
  • EUR 705.60
  • EUR 316.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with Cy3.

Immunoglobulin G (IgG) Polyclonal Antibody (Horse), HRP

4-PAA544Eq01-HRP
  • EUR 402.00
  • EUR 3762.00
  • EUR 1052.40
  • EUR 511.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with HRP.

Immunoglobulin G (IgG) Polyclonal Antibody (Horse), APC

4-PAA544Eq01-APC
  • EUR 441.60
  • EUR 4318.80
  • EUR 1191.60
  • EUR 566.40
  • EUR 274.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with APC.

Immunoglobulin G (IgG) Monoclonal Antibody (Horse), FITC

4-MAA544Eq22-FITC
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with FITC.

Immunoglobulin G (IgG) Polyclonal Antibody (Horse), FITC

4-PAA544Eq01-FITC
  • EUR 376.80
  • EUR 3478.80
  • EUR 976.80
  • EUR 476.40
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with FITC.

Goat Anti Horse Igg (H/L) Polyclonal Antibody,Alk. Phos.

DPBT-67134GH 1 mg
EUR 696

Horse D-Dimer ELISA Kit

20-abx150441
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Immunoglobulin G (IgG) Monoclonal Antibody (Horse), Biotinylated

4-MAA544Eq22-Biotin
  • EUR 339.60
  • EUR 2476.80
  • EUR 753.60
  • EUR 409.20
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with Biotin.

Immunoglobulin G (IgG) Polyclonal Antibody (Horse), Biotinylated

4-PAA544Eq01-Biotin
  • EUR 393.60
  • EUR 3236.40
  • EUR 943.20
  • EUR 484.80
  • EUR 271.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Immunoglobulin G (IgG). This antibody is labeled with Biotin.

Horse Leptin(LEP) ELISA kit

CSB-EL012870HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Horse Leptin (LEP) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Leptin(LEP) ELISA kit

1-CSB-EL012870HO
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Horse Leptin(LEP) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Leptin (LEP) ELISA Kit

20-abx150465
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Horse Leptin (LEP) ELISA Kit

SEA084Eq-10x96wellstestplate 10x96-wells test plate
EUR 6259
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Leptin (LEP) in serum, plasma and other biological fluids.

Horse Leptin (LEP) ELISA Kit

SEA084Eq-1x48wellstestplate 1x48-wells test plate
EUR 620.63
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Leptin (LEP) in serum, plasma and other biological fluids.

Horse Leptin (LEP) ELISA Kit

SEA084Eq-1x96wellstestplate 1x96-wells test plate
EUR 835.18
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Leptin (LEP) in serum, plasma and other biological fluids.

Horse Leptin (LEP) ELISA Kit

SEA084Eq-5x96wellstestplate 5x96-wells test plate
EUR 3398.29
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Leptin (LEP) in serum, plasma and other biological fluids.

Horse Leptin (LEP) ELISA Kit

4-SEA084Eq
  • EUR 6319.20
  • EUR 3338.40
  • EUR 835.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Horse Leptin (LEP) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Horse Leptin,LEP ELISA kit

YLA0052HO-48T 48T
EUR 525

Horse Leptin,LEP ELISA kit

YLA0052HO-96T 96T
EUR 645

Horse insulin (INS) ELISA kit

CSB-EL011742HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Horse insulin (INS) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse insulin (INS) ELISA kit

1-CSB-EL011742HO
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Horse insulin (INS) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Albumin(Alb) ELISA Kit

CSB-E16205Hs-24T 1 plate of 24 wells
EUR 198
Description: Quantitative competitive ELISA kit for measuring Horse Albumin (Alb) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Albumin(Alb) ELISA Kit

1-CSB-E16205Hs
  • EUR 667.20
  • EUR 4634.40
  • EUR 2472.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative competitive ELISA kit for measuring Horse Albumin(Alb) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Insulin (INS) ELISA Kit

abx576559-96tests 96 tests
EUR 1036.8

Horse Thrombin(TM) ELISA Kit

QY-E120058 96T
EUR 573.6

Horse Albumin(Alb) ELISA Kit

YLA0068HO-48T 48T
EUR 525

Horse Albumin(Alb) ELISA Kit

YLA0068HO-96T 96T
EUR 645

Horse Insulin(INS)ELISA Kit

YLA0021HO-48T 48T
EUR 525

Horse Insulin(INS)ELISA Kit

YLA0021HO-96T 96T
EUR 645

Horse ferritin(FE)ELISA Kit

YLA0066HO-48T 48T
EUR 525

Horse ferritin(FE)ELISA Kit

YLA0066HO-96T 96T
EUR 645

Horse Gelsolin(GSN) ELISA kit

CSB-EL009965HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Horse Gelsolin (GSN) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Gelsolin(GSN) ELISA kit

1-CSB-EL009965HO
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Horse Gelsolin(GSN) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Myoglobin(MB) ELISA kit

CSB-EL013529HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Horse Myoglobin (MB) in samples from serum, plasma, tissuehomegenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Myoglobin(MB) ELISA kit

1-CSB-EL013529HO
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Horse Myoglobin(MB) in samples from serum, plasma, tissuehomegenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse cortisol (COR) ELISA kit

CSB-EQ027342HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Horse cortisol (COR) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse cortisol (COR) ELISA kit

1-CSB-EQ027342HO
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Horse cortisol (COR) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse thyroxine (T4) ELISA kit

CSB-EQ027512HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitative competitive ELISA kit for measuring Horse thyroxine (T4) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse thyroxine (T4) ELISA kit

1-CSB-EQ027512HO
  • EUR 722.40
  • EUR 5085.60
  • EUR 2707.20
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative competitive ELISA kit for measuring Horse thyroxine (T4) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse estradiol (E2) ELISA kit

CSB-EQ027953HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Horse estradiol (E2) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse estradiol (E2) ELISA kit

1-CSB-EQ027953HO
  • EUR 722.40
  • EUR 5085.60
  • EUR 2707.20
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Horse estradiol (E2) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Tryptase (TPS) ELISA Kit

SEB070Eq-10x96wellstestplate 10x96-wells test plate
EUR 6596.72
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Tryptase (TPS) in serum, plasma and other biological fluids.

Horse Tryptase (TPS) ELISA Kit

SEB070Eq-1x48wellstestplate 1x48-wells test plate
EUR 648.43
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Tryptase (TPS) in serum, plasma and other biological fluids.

Horse Tryptase (TPS) ELISA Kit

SEB070Eq-1x96wellstestplate 1x96-wells test plate
EUR 874.91
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Tryptase (TPS) in serum, plasma and other biological fluids.

Horse Tryptase (TPS) ELISA Kit

SEB070Eq-5x96wellstestplate 5x96-wells test plate
EUR 3577.09
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Horse Tryptase (TPS) in serum, plasma and other biological fluids.

Horse Tryptase (TPS) ELISA Kit

4-SEB070Eq
  • EUR 6657.60
  • EUR 3517.20
  • EUR 876.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Horse Tryptase (TPS) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Horse Ubiquitin ELISA Kit (Ub)

RK00775 96 Tests
EUR 625.2

Horse Ghrelin(GHRL)ELISA Kit

YLA0003HO-48T 48T
EUR 525

Horse Ghrelin(GHRL)ELISA Kit

YLA0003HO-96T 96T
EUR 645

Horse Cortisol(COR) ELISA Kit

YLA0026HO-48T 48T
EUR 525

Horse Cortisol(COR) ELISA Kit

YLA0026HO-96T 96T
EUR 645

Horse Ubiquitin,Ub ELISA Kit

YLA0051HO-48T 48T
EUR 525

Horse Ubiquitin,Ub ELISA Kit

YLA0051HO-96T 96T
EUR 645

Horse Catalase (CAT)ELISA Kit

YLA0057HO-48T 48T
EUR 525

Horse Catalase (CAT)ELISA Kit

YLA0057HO-96T 96T
EUR 645

Horse Hepcidin(HAMP) ELISA kit

CSB-EL010124HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Horse Hepcidin (HAMP) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Hepcidin(HAMP) ELISA kit

1-CSB-EL010124HO
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Horse Hepcidin(HAMP) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Prolactin(PRL) ELISA kit

CSB-EL018724HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Horse Prolactin (PRL) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Prolactin(PRL) ELISA kit

1-CSB-EL018724HO
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Horse Prolactin(PRL) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Clusterin(CLU) ELISA kit

CSB-EL005595HO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Horse Clusterin (CLU) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Horse Clusterin(CLU) ELISA kit

1-CSB-EL005595HO
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Horse Clusterin(CLU) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Horse Eotaxin (CCL11) ELISA Kit

20-abx150443
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Horse Hemoglobin (HB) ELISA Kit

20-abx150446
  • EUR 6448.80
  • EUR 3441.60
  • EUR 811.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

IL5 ELISA Kit (Horse) (OKCD00140)

OKCD00140 96 Wells
EUR 1090.8
Description: Description of target: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.By similarity ;Species reactivity: Horse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 5.9 pg/mL

IL2 ELISA Kit (Horse) (OKCD00739)

OKCD00739 96 Wells
EUR 1090.8
Description: Description of target: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. ;Species reactivity: Horse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 10.5 pg/mL

EPO ELISA Kit (Horse) (OKCD01439)

OKCD01439 96 Wells
EUR 1090.8
Description: Description of target: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.;Species reactivity: Horse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 11.6 pg/mL

IL6 ELISA Kit (Horse) (OKCD01462)

OKCD01462 96 Wells
EUR 1090.8
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Horse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 3.0 pg/mL

LEP ELISA Kit (Horse) (OKCD01466)

OKCD01466 96 Wells
EUR 1090.8
Description: Description of target: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity. In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides. In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by increasing chemotaxis and the secretion of oxygen radicals. Increases phagocytosis by macrophages and enhances secretion of pro-inflammatory mediators. Increases cytotoxic ability of NK cells. Plays a pro-inflammatory role, in synergy with IL1B, by inducing NOS2 wich promotes the production of IL6, IL8 and Prostaglandin E2, through a signaling pathway that involves JAK2, PI3K, MAP2K1/MEK1 and MAPK14/p38. In adaptive immunity, promotes the switch of memory T-cells towards T helper-1 cell immune responses. Increases CD4+CD25- T-cell proliferation and reduces autophagy during TCR (T-cell receptor) stimulation, through MTOR signaling pathway activation and BCL2 up-regulation.;Species reactivity: Horse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.251 ng/mL

TNF ELISA Kit (Horse) (OKCD01489)

OKCD01489 96 Wells
EUR 1090.8
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.;Species reactivity: Horse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 2.7 pg/mL

AFP ELISA Kit (Horse) (OKCD04403)

OKCD04403 96 Wells
EUR 1090.8
Description: Description of target: ;Species reactivity: Horse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 2.51 pg/mL
The SaToWIB routines rank profile pairs in line with numerical similarity on foundation of an goal operate. It’s proven that the rank (as decided by rating) is an indicator of fraud in that the precise fraud instances can have increased rank than if there have been no relationship between rank and rating. The paper additionally feedback on the usage of multivariate statistics and discusses the necessity for growth of formal exams for manipulation in view