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November 11, 2020
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Evaluating the bioequivalence of metronidazole tablets and analyzing the effect of in vitro dissolution on in vivo absorption based on PBPK modeling.

Evaluating the bioequivalence of metronidazole tablets and analyzing the effect of in vitro dissolution on in vivo absorption based on PBPK modeling.

Metronidazole, a BCS class I , could possibly be waived primarily based on the BCS rules, thus enabling in vitro dissolution knowledge as a surrogate of BE research. Nevertheless, the impression of dissolution profiles of metronidazole tablets on the in vivo efficiency has by no means been studied systematically. So the purpose of the current research was to […]

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